Etoposide phosphate: what, why, where, and how?
Aug 04, · What is etoposide? Etoposide is used to treat small cell lung cancer. It is usually given in combination with other cancer medicines. Etoposide may also be used for purposes not listed in this medication nicedatingusa.com names: Etopophos, Vepesid, Eposin, Pms-Etoposide, Dom-Etoposide. Aug 04, · Etoposide is used to treat cancer of the lung or testicles. It is usually given with other cancer medicines in a combination chemotherapy. Etoposide may also be used for purposes not listed in this medication nicedatingusa.com class: Mitotic inhibitors.
Medically reviewed by Drugs. Last updated on Oct 17, Etoposide injection also known as VP is used in combination with other cancer what is etoposide used for to treat cancer of the testicles and small cell lung cancer.
It is also sometimes used etoposive treat some other kinds of cancer in both males and females. Etoposide belongs to the group of medicines known as antineoplastic agents. The exact way that etoposide acts against cancer is not known. However, it seems to interfere with the growth of the cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by etoposide, other effects will also occur.
Some of these may be serious and must be whqt to your doctor. Other effects, etpposide hair loss, may not be serious but may cause concern. Some effects may not occur until months or years after the medicine is used. Before you begin treatment with etoposide, you and your doctor should talk about the benefits of etoposide as well as the risks of using it. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do.
This is a decision you and your doctor will make. For etoposide, the usee should be considered:. Tell your doctor if you have ever had any unusual or allergic reaction to etoposide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals.
For non-prescription products, read the label or package ingredients carefully. Appropriate studies have not been performed on the relationship of age to the effects of etoposide injection in the pediatric population. Safety and efficacy have not been established. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of etoposide injection in the elderly.
However, elderly patients are more likely to have unwanted side effects eg, infection, nausea and vomiting, hair lossand have age-related kidney, liver, or heart problems, which may require caution in elderly patients receiving etoposide injection. There are no adequate studies in women for determining infant hsed when using this medication during breastfeeding.
Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In how to cure bad gas smell cases, your doctor may want to change the dose, or other precautions may be necessary. When etoposice are receiving etoposide, it is especially important that your healthcare professional know if you are taking any of the medicines listed below.
The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using etoposide with any of the following medicines is not recommended. Your doctor may decide not to etopoaide you with this medication or change some what is etoposide used for the other medicines you take.
Using etoposide how to draw one direction lyrics any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.
Using alcohol or tobacco with certain medicines may also cause interactions to occur. Using etoposide with any of the following may cause an increased risk of certain side effects but may be how to apply cat makeup in some cases. If used together, your doctor may change the dose or how often you use etoposide, or give you special instructions about the use of food, alcohol, or tobacco.
The presence of other medical uxed may affect the use of etoposide. Make sure you tell your doctor if you have any other medical problems, especially:.
A nurse or other trained health professional will give you etoposide in a hospital or cancer treatment center. Etoposide is given through a needle placed in one of your veins. The medicine must be injected slowly, so your IV tube will need to stay in place for 30 to 60 minutes.
Etoposide is sometimes given together with certain other medicines. If you are using a combination of medicines, make sure that you take each one at the proper time and do not mix them. If you are taking some of these medicines by mouth, ask your doctor to help you plan a way to remember to take your medicines at the right times. Etoposide often causes nausea, vomiting, and loss of appetite, which may be severe. However, it is very important that you continue to receive the medicine, even if you begin to feel ill.
Ask your doctor for ways to lessen these effects. It is very important that your doctor check your progress at regular visits to make sure that etoposide is working properly. Blood etopoxide may be needed to check for unwanted effects. Using etoposide while you are pregnant can harm your unborn baby.
Use an effective form of birth control to keep from getting pregnant during treatment and for at how to make an anti static bracelet 6 months after your last dose. If you think you have become pregnant while using the medicine, tell your doctor right away. Etoposide may also cause birth defects if the father is using it when his sexual partner becomes pregnant.
Men using etoposide should use condoms as a form of birth control during treatment and for at least 4 months after the last dose of etoposide. A man intending to father a child should stop using etoposide and check with his doctor right away. Etoposide can temporarily lower the number of white blood cells in your blood, increasing the chance of your getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If etpooside occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:.
Etoposide may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you have chills, fever, lightheadedness, dizziness, or fainting, fast, pounding heartbeat, swelling of the face, tongue, and throat, or trouble breathing after you receive the medicine.
Injection site reactions may occur while you are receiving etoposide. Tell your doctor right away if you notice swelling, pain, or redness at the injection site. Etoposide may cause leukemia cancer iis the blood or bone marrow in rare cases. Talk with your doctor about any concerns you have about this. Talk with your doctor before getting flu shots or other vaccines while you are receiving etoposide because there are certain vaccines that you ror not receive.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription over-the-counter [OTC] medicines and herbal or vitamin supplements.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:.
Etoposide often causes a temporary loss of hair. After treatment with etoposide has ended, normal hair growth should return. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call iis doctor for medical advice uxed side effects. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Intravenous route Solution Severe myelosuppression with resulting infection or bleeding may occur with etoposide.
Detailed Etoposide dosage information. Etoposide side effects more detail. Drug Status Availability Prescription only Rx.
Mylan Pharmaceuticals Inc. Accord Healthcare Inc. Drug Class. Mitotic inhibitors. Related Drugs. Review this Drug No reviews. Subscribe to our newsletters.
Aug 04, · Etoposide is used to treat cancer of the lung or testicles. It is usually given with other cancer medicines in a combination chemotherapy. Etoposide . While etoposide is active in the treatment of many cancers and is widely used, it has a number of limitations due to its lack of water nicedatingusa.com by: What Etoposide Is Used For: Testicular, bladder, prostate, lung, stomach, and uterine, cancers. Hodgkin's and non-Hodgkin's lymphoma, mycosis fungoides, Kaposi's sarcoma, Wilm's tumor, rhabdomyosarcoma, Ewing's sarcoma, neuroblastoma, brain tumors. It also may be given as high-dose therapy in bone marrow transplant setting.
The podophyllotoxin derivatives etoposide and teniposide are active in the treatment of a variety of malignant conditions. Both represent chemical modifications of podophyllin, an extract of Podophyllum peltatum May apple, mandrake, Indian apple, wild lemon, or duck's foot , a plant long used as a folk remedy and recognized in the 19th century to be effective in the treatment of cancer.
While etoposide is active in the treatment of many cancers and is widely used, it has a number of limitations due to its lack of water solubility. Etoposide phosphate Etopophos; Bristol-Myers Squibb Company, Princeton, NJ is a water-soluble prodrug of etoposide that is rapidly and completely converted to the parent compound after intravenous dosing. The pharmacokinetic profile of etoposide after treatment with either etoposide or etoposide phosphate is identical.
Toxicity and clinical activity also are the same. Furthermore, it is not formulated with polyethylene glycol, polysorbate 80 Tween; ICI Americas, Wilmington, DE , and ethanol, and does not cause acidosis when given at high doses.
The easier-to-use etoposide phosphate represents an improved formulation of etoposide. Abstract The podophyllotoxin derivatives etoposide and teniposide are active in the treatment of a variety of malignant conditions. Publication types Review.
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